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			<h1 style="margin-top:0px;">Gene Copy Number Analysis</h1>
        
		
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                    <div class="wp"><p><b><br />
</b>Our lab has established expertise in determining genomic copy number, either as part of mutation analysis for a particular gene or to establish genomic copy number for a number of genes involved in tumor progression.</p>
<p>We also offer DNA extraction, methylation analysis and sequencing.</p>
<p>For more details or to submit samples, contact us at 416-603-5597 or <a href="mailto:info@solutionsbysequence.com?subject=query%20about%20copy%20number%20tests">info@solutionsbysequence.com</a></p>
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            <h3>Features of our Service</h3>
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                <li>Lab certified by the College of American Pathologists; our work meets high clinical standards</li>
                <li>Established expertise in both QM-PCR (Quantitative multiplex PCR) and <a href="http://www.mrc-holland.com/WebForms/WebFormMain.aspx?Tag=zjCZBtdOUyAt3KF3EwRZhNWLtcfv9pVl/tHJIM\fa9FWO8KMqctOGIoqYwxaGF9Y">MLPA</a> (Multiplex Ligation-dependent Probe Amplification).</li>
                <li>We will work with you to determine the best method for your needs</li>
                <li>Unique platform for quantitative electrophoretic analysis</li>
                <li>
                <p>Incorporation of numerous internal and external controls</p>
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            <h3><strong>QM-PCR</strong></h3>
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                <li>New QM-PCR assays can be developed to include your genes of interest.</li>
                <li>Lower cost per sample vs. MLPA</li>
                <li>Available for use on un-fragmented genomic DNA, fresh blood samples and fresh or frozen tissue from non-paraffinized sources.</li>
                <li>Approximately $25.00 per DNA sample for multiplex of 5-6 genes or exons of your choosing.</li>
            </ul>
            <p><img width="680" height="150" alt="" src="/site/ywd_solutions_by_sequence/assets/images/Qimage.gif" /></p>
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            <h3>MLPA</h3>
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                <li>Can be used on slightly fragmented genomic DNA or paraffinized tissue samples</li>
                <li><a href="http://www.mrc-holland.com/WebForms/WebFormProductList.aspx?Tag=tz2fAPIAupLbtzOGlO4GZ9o4vru9qLhUa8hxhTfGwdGEdfheTmGdKA||&amp;ProductListGroupFilter=uTtwg4kX7M2xzCLRM9Ck115pAX4RdVTn">Many kits</a> currently exist for testing various genes &amp; gene combinations</li>
                <li>Requires normal control samples from sending lab</li>
                <li>Approximately $50.00 per DNA sample for MLPA kit of 12-15 genes or exons</li>
                <li><img width="680" height="228" alt="" src="/site/ywd_solutions_by_sequence/assets/images/Mimage.gif" /></li>
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